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Availability of data and materials The dataset used in this study is publicly available from the Healthcare Cost and Utilization Project (HCUP) National Inpatient Sample (NIS) at Abbreviations AHRQ: Agency for Healthcare Research and Quality aOR: Adjusted Odds Ratio APACHE: Acute Physiology and Chronic Health Evaluation APE: Acute pulmonary edema BNP: B-type natriuretic peptide CI: Confidence interval HCUP: Healthcare Cost and Utilization Project HPA: HypothalamicPituitaryAdrenal ICD-10-CM: International Classification of Diseases, 10th Revision, Clinical Modification NIS: National Inpatient Sample NPE: Neurogenic Pulmonary Edema PEEP: Positive end-expiratory pressure SAH: Subarachnoid hemorrhage SOFA: Sequential Organ Failure Assessment References Ware LB, Matthay MA

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