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RNAScope FISH (ALI wholemount labeling) ALI cultures on transwell inserts were rinsed with 1 PBS, fixed for 30 min in 3.2% PFA (no sucrose) at room temperature, rinsed twice more with 1 PBS and stored at 4 C

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Heated tobacco products (such as Philip Morris Internationals IQOS ) are explicitly included under the tobacco law in Indonesia, too

Availability of data and materials The datasets analyzed during the current study are available in the IPUMS repository at Abbreviations NHIS: National health interview survey HR: Hazard ratio CI: Confidence interval IPUMS: Integrated public use microdata series NDI: National Death Index ICD: International classification of diseases and related health problems BMI: Body mass index CPS: Cancer prevention study TUS-CPS: Tobacco use supplement to the current population survey References Rostron BL, Corey CG, Gindi RM

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