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10.1016/j.ijbiomac.2024.131172 149 YueZ.ZhuY.ChenT.FengT.ZhouY.ZhangJ.et al (2024)

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Ongoing Research Phase 3 development programs (REDEFINE 1 and REDEFINE 2) are evaluating cagrilintidesemaglutide in obesity and type 2 diabetes populations, with cardiovascular and metabolic endpoints under active study

Common reasons include low glutathione concentration, unstable liposomes, tablet compression destroying liposomal structure, and sub-therapeutic dosing