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Sex-based differences in phagocyte metabolic profile in rats with monosodium glutamate-induced obesity

These findings reveal a hierarchical modification network architecture: The METTL3-m6A modification initiates the TGF- transcriptional cascade, the NAT10-ac4C modification stabilizes key effectors (for example, EGR3 mRNA), and the METTL1-m7G modification enhances the translational efficiency of downstream genes