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There was also friction over process

This pipeline was benchmarked against our standard GATK-based pipeline using a subset of WES samples from patients with liver disease, with a diverse set of causative genes and inheritance patterns

If NADH is also in short supply, CYB5R3s reductive activity may decline, causing a combined loss of hemoglobins oxygen-carrying function and its capacity to buffer NO ( In summary, G6PD plays a central role in shaping the redox landscape of RBCs