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First, three hairpin-structured DNA probes H 1 , H 2 and H 3 were designed, H 1 including a disulfide bond (-S-S-), H 3 labeled with a fluorophore/quencher pair

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It was also reported that a surgeon was able to use hydrogen gas to insufflate the gastro-intestinal canal to accurately determine and locate visceral injuries, avoiding unwarranted surgeries [3]