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Pharmacol Res 2007;55:224236

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Now that weve covered how bacteria and archaea can overgrow in the small intestine, lets dive into SIBO root causes - the underlying factors that, when working properly, should actually prevent SIBO

Whereas sulfenic acid and disulfides can be reversed by antioxidant systems such as the thioredoxin (Trx) or glutaredoxin (Grx) systems [231, 232], sulfinic and sulfonic acid are generally considered irreversible modifications in prokaryotes which typically lead to inactivation and aggregation of proteins

Data availability This manuscript does not have data that need to be deposited in a public database

Hypothetical research combination