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Device Type: Whether disposable or refillable, the specific model affects nicotine delivery per puff

Used in low doses like those delivered by combustible cigarettes, stimulants activate the nervous system, resulting in enhanced arousal and alertness

Now that we have an understanding of the different brain circuits, we think we can maybe develop a drug so that, when nicotine is taken at a low dose, these brain circuits can be coactivated to induce an acute aversive effect

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Baker, Amira Osman, Li-Ling Huang, and Adam O