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The production of melanin is triggered by an enzyme called tyrosinase

Pregnant or breastfeeding women, and people with certain medical conditions (like uncontrolled asthma or kidney issues) should avoid treatment

Mattevi, A., Schierbeek, A

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This PTM also occurs in mitochondria, regulating the OXPHOS and other mitochondrial functions [166]

To critically appraise mechanisms and levels of evidence ( in vitro, in vivo , clinical) for vitamin E and C, glutathione and its precursors, polyphenols (quercetin, resveratrol, curcumin), Crocus sativus carotenoids (crocin/safranal), and indirect modulators (e.g., omega-3, folinic acid), emphasizing study quality, translational relevance, and limitations