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Pernicious anaemia occurs when the immune system attacks the healthy, specialised cells of the stomach that produce the intrinsic factor

FDA Registered How Glutathione Works Glutathione competitively inhibits melanin synthesis in the reaction of tyrosinase and L-DOPA by interrupting L-DOPA's ability to bind to tyrosinase during melanin synthesis

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Although glucose is the principal energy fuel of the brain in normal conditions, lactate can be an alternative source during hypoglycemia and because of mitochondrial shifts in redox state or ischemia

Since the transgene expressed in these mice is expressed in glutamatergic cells and enhances their excitability, it is to be expected that they would show abnormalities in glutamate homeostasis