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Studies have detected diacetyl in up to 75% of flavored e-cigarettes tested, even in products labeled "diacetyl-free." The American Lung Association has expressed serious concern about these flavoring compounds and their potential to cause permanent respiratory damage

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Data availability The datasets generated and analyzed during the current study were available from the corresponding author on reasonable request

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This may seem like something of an irritating limitation, but realistically youll very rarely (if ever) run into this in practice