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Over one billion people are current tobacco users, and the majority of them are addicted to nicotine, according to the World Health Organisation (WHO)

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This is of particular concern given the independent and inverse association between age of smoking initiation with chronic disease risk.22 As in the UK Biobank, daily cigarette consumption is lower in women than in men in most populations studied, although the difference appears to have diminished over time.1315 For example, women smoke on average four cigarettes per day less than men in the 16 GATS countries.13 We have previously reported that women from the Asia-Pacific region have smoked fewer cigarettes than men: an average of 10 vs 15 cigarettes per day in Asia and 16 vs 18 cigarettes per day in Australia and New Zealand.14 The US 2004 National Health Interview Survey reported the mean consumption of cigarettes per day as 18.1 in men and 15.3 in women.15 Finally, the 2010 smoking statistics in England estimated men to smoke 13.3 cigarettes a day, compared with 12.1 for women.21 Sex differences in the prevalence of smoking The prevalence of smoking has declined substantially in most parts of the world