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These models are visually categorized by type and mechanism in Figure 6, which highlights their common outcome: ovarian dysfunction driven by oxidative stress

Studies have shown that anthocyanins can modulate signaling pathways involved in oxidative stress, including the Nrf2 pathway

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AST is found in mitochondria and cytoplasm, while ALT is found in cytoplasm but not mitochondria 36

In addition, continuous telemetric EEG recordings and video monitoring showed increased seizure and interictal spike activity in CX-deficient mice as compared to wildtype mice, without causing a change in the severity of status epilepticus (Deshpande et al., 2020)

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