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A better understanding of the epidemiology, risk factors, mechanisms, clinical presentation, management, and prevention of this condition is critical to optimize the use of vancomycin and minimize the risk of nephrotoxicity in patients

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Turk J Biol 36:8592 Pillco A (2011) Evaluacin toxicolgica de mezclas complejas mediante ensayos alternativos a la experimentacin animal de genotoxicidad, mutagenicidad y ecotoxicidad (Toxicological evaluation of complex mixtures employing genotoxicity, mutagenicity and ecotoxicity assays as an alternative to animal testing) Doctoral thesis, Autonomous University of Madrid, p 173 Rank J, Nielsen MH (1998) Genotoxicity testing of wastewater sludge using the Allium cepa anaphase-telophase chromosome aberration assay

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