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2007 Mar 15;120(6):13761377

This paper shows that, because smoking and passive smoking facilitate the spread of TB and the transition from infection to active TB, reducing tobacco use is an important key to achieving the millennium development goals for TB. Those goals are to cut TB mortality in half from 1980 to 2015

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Early Concepts Date Back to the 1960s - The first patent for a smokeless, flavoured vapour device was filed in 1963 by Herbert A