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Ferroptosis and DCM DCM, characterized by diastolic and systolic dysfunction, left ventricular hypertrophy, myocyte hypertrophy, and fibrosis (93), is a major cause of heart failure in patients with diabetes

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Between the baseline and the 45-min scan, there was a mean 269% increase in GSH/Cr (240% increase in absolute GSH)

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In vivo studies showed that specific deletion of myeloid cell Gpx4 in mice exhibited SLE-like clinical manifestations, which could be alleviated by treatment with liproxstatin-1, an ferroptosis inhibitor, and attenuated disease progression