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Diagnosis is made by exclusion of alcohol abuse and other causes of liver disease (HBV-related hepatitis, HCV-related hepatitis, autoimmune liver diseases, polycystic ovary syndrome, drug-induced liver disease and congenital causes such as hereditary hemochromatosis, Wilsons disease, alpha-1 antitrypsin deficit)

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NAC may be beneficial for adults seeking additional antioxidant support, healthy liver function, and support for normal detoxification pathways

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Finally, the clinical studies summarized used collagen (bovine or animal sources such as fish, collagen peptides, and hydrolyzed collagen, where some test materials were commercially available products while others used multiple custom formulations), which are noted in the brief descriptions above

Glutathione is known to change eumelainin (dark-brown pigment) into pheomelanin (reddish yellow), thus reducing hyperpigmentation and evening out blemishes in the skin