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Firstly, the sample of smokers was judiciously selected based on the geographical representation, but not a random sample of the entire smoking population in Shanghai, and the 1104 smokers in this study was a relatively smaller sample in comparison with the large number of tobacco smokers in Shanghai, which limited the generalization of findings in this study

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In essence, there was no need for it, and the convenience it offered is very relative

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[8] [9] [10] [12] The Spanish introduced tobacco to Europeans in about 1528, and by 1533, Diego Columbus mentioned a tobacco merchant of Lisbon in his will, showing how quickly the traffic had sprung up