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LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors

10.1038/sj.ejhg.5201419 4

Knockdown of COPZ1 in GBM cells leads to increased expression of nuclear receptor coactivator 4 (NCOA4), and inhibition of FTH1 leads to ferritin degradation, resulting in excessive accumulation of intracellular Fe 2+ , leading to ferroptosis (88)

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