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Those women who experienced a worsening of depressive and/or stress symptoms during the first 12 weeks postpartum were at an increased risk of smoking relapse by 24 weeks

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Acknowledgements We thank all participants, the complete staff at the NAKO study centers, the data management and integration center, and the NAKO head office who enabled the conduction of the study and made the collection of all data possible

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'Why smoking impairs the ability to learn about safety is not clear, but one possibility is that smoking changes neurotransmitter balances in the brain, which are necessary for successful safety learning.' Dr Haaker and his colleagues now hope to unravel the mechanism underlying this effect with the hope of developing new treatments and perhaps even new drugs

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