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Conversely, deubiquitinases/DUBs remove ubiquitin chains from substrate proteins, counteracting the activity of E3 ligases, thereby stabilizing the targeted proteins

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Choi F D, Sung C T, Juhasz M L, et al

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Medicine interactions NCCIH advises people taking any medicine to discuss grape seed extract with a health professional

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Excessive ionophore administration can overwhelm these defenses, leading to systemic copper poisoning, characterized by hepatotoxicity, nephrotoxicity, and hematopoietic suppression [239]

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