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Future studies will be of interest to assess whether the airway epithelial structure and function of mitochondria differs between in young non-smoking individuals who are non-susceptible and susceptible to develop COPD

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In CIA and AIA mice, CS enhanced Th17 cells through polycyclic aromatic hydrocarbons (PAHs) from CS engagement with the aryl hydrocarbon receptor (AHR) (23, 25)

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Physicians have thus been cued not to talk with the patient about stopping smoking but rather to prescribe an additional medication, often one to treat an adverse effect of smoking