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Metabolism of all ECs is characterized by a reliance on glycolysis for ATP generation in both proliferating and quiescent states, with a notable decrease in glycolytic flux during quiescence (De Bock et al, 2013b

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TrxR works together with thioredoxin (Trx) and reduced coenzyme II (NADPH) to form an antioxidant system [122,123]

Gueniche A, Valois A, Kerob D, Rasmont V, Nielsen M (2022) A combination of Vitreoscilla filiformis extract and Vichy volcanic mineralizing water strengthens the skin defenses and skin barrier

the isocitrate dehydrogenase (IDH), which converts isocitrate to -ketoglutarate

Importantly, the notochord is the main signaling center that directs the patterning of the surrounding tissues during early development (Pourqui et al., 1993