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Anti-inflammatory lobane and prenyleudesmane diterpenoids from the soft coral Lobophytum varium

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Furthermore, Keap1, a cysteine rich protein which binds to NRF2 and regulates oxidative and electrophilic stress, was co-localized with intracellular misfolded protein inclusions in motor neurons in the spinal cord of ALS patients

10.1016/j.bpj.2019.05.013 74 HuangS.MoX.WangJ.YeX.YuH.LiuY

LiQLuQBotteroVEstepaGMorrisonLMercurioFet alEnhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1)