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Masuda, M., Sawa, M

22, G/D-CuP group exhibited a significantly reduced proportion of CD86-positive cells compared to the NC group

Villareal DT, Miller BV, Banks M, Fontana L, Sinacore DR, Klein S

In human skin fibroblasts, Nrf2-driven antioxidant enzyme expression translated into: Reduced intracellular ROS Improved mitochondrial membrane potential Protection against senescence-associated cell damage [36] In human gingival and periodontal stem cells, Epitalon significantly reduced aging biomarkers such as p16 and p21, decreased ROS levels, and preserved mitochondrial function, even under stress [42]

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