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Hypercalcemia.Pathophysiological aspects

Prior to embedding in Agar 100 Resin (Agar Scientific, Stansted, UK) the material was post fixed in 2% OsO4 (buffered with 0.05 M sodium cacodylate, pH 7.3) and dehydrated in a graded acetone series

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10.1002/cncr.31248 81 MakinT

Notably, mitochondria harbour a labile iron pool with strong redox activity [41], positioning these organelles as a critical hub for iron-dependent oxidative metabolism