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COA Independent Lab Services Horizon Analytical Issued Research Use Only Chromatogram Detection 220 nm 0 min5101520 min Analyst Aleksey Yevtodiyenko PhD Research and Formulation Chemist Issuing Lab Horizon Analytical Independent third-party [email protected]

doi: 10.1016/j.iotech.2022.100070 66 StortiPVescoviniRCostaFMarchicaVToscaniDDalla PalmaBet al

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ethers, acetals, ketones, quinones, aldehydes, peroxides A61K47/14Esters of carboxylic acids, e.g

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Activation of aerobic glycolysis-related bypass pathways Increased glycolysis simultaneously activates multiple self-associated bypass pathways, among which the PPP provides the raw material for purine and pyrimidine nucleotide synthesis and maintains redox homeostasis for cancer cell growth, which largely depends on the activity of glucose-6-phosphate dehydrogenase (G6PD), as it catalyzes the first step of the glucose-6-phosphate shift to the PPP [46]