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Recent single-cell RNA sequencing (scRNA-seq) studies (287, 288) have further revealed that in CKD, PT cells downregulate SLC7A11 and GPX4 expression, while interstitial fibroblasts upregulate pro-ferroptotic genes (e.g., ACSL4 and LOX), suggesting cell type-specific ferroptosis programs that drive fibrosis

doi: 10.1038/nrclinonc.2016.217 192 KrnetaTGillgrassAPoznanskiSChewMLeeAJKolbMet al

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Furthermore, the number of CD8 + T cells was increased in the DRG of paclitaxel-treated mice, contributing to recovery from neuropathic symptoms via IL-10-mediating signaling (Krukowski et al., 2016)

Wenn Fremdkrper in den Krper eindringen, werden diese von weien Blutkrperchen aufgenommen und mit Hilfe von Chemikalien in sogenannte freie Radikale umgewandelt