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Description

It is generally considered safe for research purposes when used as intended within a controlled environment

Blood-brain barrier breakdown in acute and chronic cerebrovascular disease

Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD

Ramezanian I, Baradaran E, Majidinia S, Ramezanian S, Jafari M

However, preclinical studies demonstrate therapeutic effects with once-daily or even less frequent administration, suggesting tissue distribution, receptor binding, or cellular signaling effects extend beyond plasma clearance