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Disappointingly, in the subsequent Phase 3 trial in 861 patients with severe traumatic brain injury, a single intravenous injection of 150 mg of dexanabinol administered within 6 hours of the injury failed to produce significant improvement versus placebo on the Glasgow Coma Scale at 6 months post-injury [114]

Induction was more pronounced in cynomologus than in patas monkeys, with no apparent sex difference and with a pattern of results that is consistent with that previously seen in rodents

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[42] However, one should note that glutathione mainly affects the melanin indices and ultraviolet spots in the sun-exposed areas

[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Chen L, Tuo B, Dong H