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10.1016/j.neulet.2012.09.044 316 VianaF.Van den BoschL.MissiaenL.VandenbergheW.DroogmansG.NiliusB.et al (1997)

Furthermore, the mutator phenotype associated with defective MutL activity was suppressed when a non-functional recB allele, derived from ET-37 meningococcal strains, replaced the functional recB allele, suggesting that in MutL-deficient strains, hypermutation mostly arises during post-replicative DNA synthesis associated with the activity of the RecBCD recombination pathway ( N

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For instance, miR-16 -loaded minicell is in clinical investigation for the treatment of malignant pleural mesothelioma (229)