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doi: 10.1080/00365510050184994

To test this hypothesis, we first validated the RNA-seq results by RT-qPCR experiments: cytosolic RPGs ( RPS6A / RPS6B , RPS22A , RPL38 , RPL31A ), as well as a mitochondrial RPG ( MRPL50 ), were significantly downregulated in the context of V-ATPase-dependent autophagy ( Fig

CD38_targeting monoclonal antibodies (mAbs), including daratumumab (DARA) and isatuximab (ISA), exert antitumor activity through direct cytotoxicity and immune modulation

While safety was established, efficacy for weight loss did not meet clinical trial success criteria

TABLE 2 Characteristics of the included studies

- Hydroxocobalamin offers a longer-lasting effect and is more suitable for therapeutic use