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From the above experiments, total enzymatic rates (actual enzymatic plus non-enzymatic rates) were obtained

Cell Imaging/Staining RT-PCR Cell Proliferation/Viability Assay Cell Migration/Invasion Assay Cell Proliferation/Viability Assay All DNA/RNA Synthesis Isoforms More Biological Activity antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis

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Body weight was normal and all the subjects were on a standard balanced diet

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Combined checkpoint inhibitor therapy causing diabetic ketoacidosis in metastatic melanoma