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Melatonin supplementation: new insights into health and disease

Cancer Cell 43 , 937954.e9 (2025)

Rapidly cutting down or stopping the medication may result in irritability, nightmares, vomiting, confusion, fatigue, and suicidal thoughts

Inhibition of Calcitriol Synthesis The progressive loss of functioning nephrons and increased production of FGF23 are mainly responsible for the reduction in renal calcitriol synthesis, favoring the development of hyperparathyroidism