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The proportion of young people having smoked in the past 30 days stayed relatively low for boys and girls 11, 12, and 13 years old, but had already begun to climb steeply by age 14 (9.5% of girls and 9.9% of boys)

The chemicals in cigarette smoke damage blood vessels, leading to atherosclerosis (hardening and narrowing of the arteries) and an increased risk of blood clots

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As with drugs such as cocaine and heroin, nicotine activates the brains reward circuits and also increases levels of the chemical messenger dopamine, which reinforces rewarding behaviors

Tobacco is a major cause of preventable death globally, and it is the leading risk factor for cancer, heart disease, diabetes, and lung disease (categorically known as non-communicable diseases)

Under pathological conditions, excessive free radicals further aggravate diseases through oxidative stress