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To examine whether p21 expression was sufficient to fully recapitulate the functions of p53 in ferroptosis suppression in HT-1080 cells, we generated cell lines expressing Flag-tagged CDKN1A under the control of a doxycycline (Dox)-inducible promoter, denoted p21 Dox

These symptoms are frequently misattributed to lifestyle and stage of life, such as work-related stress, pregnancy, menopause, ageing and dementia[15]

Different effects of Danefukang Decoction on the expression of MMP-2 and VEGF in eutopic and ectopic endometrium of adenomyoma mice

Although we successfully obtained the COP1-bound DDD complex, as judged by SDS-PAGE, the two largest populations were those without COP1 bound, suggesting that COP1 dissociates from the DDD complex

The benzopyran 37 (HFI-419) enhances spatial working memory in rats and the inhibition of IRAP by 37 increased DSD prior to peak dendritic growth in hippocampal neurons (Seyer et al., 2020)