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It was shown that Ser16 is phosphorylated upon glucagon stimulation via PKA activation (Abita et al, 1976

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Verma P, Khatun R, Jew KA et al (2025) Therapeutic potential of small peptides in Alzheimers disease: advances in memory restoration and targeted delivery systems

Trends Neurosci 32:421431 Allen NJ, Bennett ML, Foo LC et al (2012) Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors