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Meanwhile, the latest review paper also emphasized the correlations between neuroinflammation and energy metabolism, focusing on the inflammatory cytokines and the activation of immune cells, extend to energy metabolism dysregulation and neural cell damage (14)

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Cell 120: 237248 Mannava S, Grachtchouk V, Wheeler LJ, Im M, Zhuang D, Slavina EG, Mathews CK, Shewach DS, Nikiforov MA (2008) Direct role of nucleotide metabolism in CMYCdependent proliferation of melanoma cells

In cell lines selected for the resistance to topoisomerase II-inhibiting drugs the activity or the quantity of this enzyme are reduced [54]

Dysregulation of iron metabolism in COVID-19-related PD Iron metabolism impairment, a significant contributor to PD [91, 92], has been extensively established in a significant fraction of COVID-19 patients in response to SARS-CoV-2 infection [93,94,95], which corresponds with the risk of severe and fatal COVID-19 illness

Standard curves were generated by using purchased standards (Cayman Chemical, Ann Arbor, MI, United States), and those made in-house were validated through NMR and MS analysis as previously described (Tan et al., 2006)