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KD used to treat refractory seizures in children was leading to the appearance of kidney stones 13,26

Interestingly, TQ shows a concentration-dependent behavior, it acts as an antioxidant at low doses while exhibiting pro-oxidant effects at higher concentrations [14]

11 The F.D.A

Data-driven prevention

Currently, the relationship between muscle damage, oxidative stress and other systems of proteolysis such as apoptosis are poorly understood

An initial gradient of methanol: dichloromethane (0-25% over 10 min) was used, followed by a second gradient of chloroform:methanol:water (35:14:1, isocratic over 15 min)