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Positively charged PPCA sequestered and cleared exRNA, while BGN@Be neutralized VEGF activity (Figure 8D), thereby inhibiting both factor function and upstream recruitment and ultimately suppressing neurovascularization at the osteochondral interface

doi: 10.17219/acem/41149 60 ParhamCChiricaMTimansJVaisbergETravisMCheungJet al

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The anabolic actions of IGF1 have been exploited for therapeutic purposes by using IGF1 administration to treat short children who are resistant to the growth promoting effects of growth hormone