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In light of such data, patients are advised not to smoke cigarettes for a minimum of 4 weeks prior to orthopaedic surgery and continue to abstain post-surgery, in order to minimise complications, facilitate maximal bone healing and reduce aseptic loosening [13, 14]

We carried out random effects meta-analysis using RevMan version 5 to estimate pooled risk estimates

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In some areas, the format may vary depending on the local law, tax or interests of consumers

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Such policies are not in place in some locations because of concerns that bans would decrease business, and because of successful lobbying to Congress and by donations to candidates, political parties, and action groups