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An alternative hypothesis is depicted on the right, in which inhalation of chemicals common in e-cigarette aerosols (propylene glycol, glycerin, nicotine, or THC) alters the inflammatory state of the lungs, including changing alveolar macrophages to a proinflammatory phenotype with the release of inflammatory cytokines (indicated by yellow circles), such that a second hit causes a pathologic inflammatory response

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Today he is a consultant for the company and continues to defend the use of these devices for adults who wish to quit smoking

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Keep your hands busy Many smokers miss the physical habit of holding a cigarette