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Molecular signaling and dysfunction of the human reactive enteric glial cell phenotype: implications for GI infection, IBD, POI, neurological, motility, and GI disorders

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Acetyl-l-carnitine is a first-in-class epigenetic regulator of genes involved in analgesic action such as the metabotropic glutamate 2 [mGlu2] receptor gene, neurotrophic factors, and antioxidant enzymes (e.g., superoxide dismutase) (Fig

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Ng CM, Blackman MR, Wang C, Swerdloff RS

Many of these processes, however, are impractical for industrial-scale production because they involve several time-consuming phases