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successfully infect host cells like neutrophils and macrophages

At neutral to alkaline pH (above 7), deamidation proceeds through a cyclic imide intermediate that produces a mixture of normal and isomerized products

Doxorubicin generates oxidative stress, damages mitochondria in heart cells, and triggers apoptosis (programmed cell death)

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Metabolism and Bioavailability Clinical trials in humans indicate that the systemic bioavailability of orally administered curcumin is relatively low (3-5) and that mostly metabolites of curcumin, instead of curcumin itself, are detected in plasma or serum following oral consumption (6, 7)