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Dry eye syndrome is more common in smokers and can be exacerbated by smoke irritation

An additional source of ROS in smokers is cigarette smoke itself, which contains high levels of ROS such as superoxide anion, hydrogen peroxide, and hydroxyl radicals [108]

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A blunt uses a thick cigar or blunt wrap, often made from tobacco leaf paper or novelty papers, and contains more ground cannabis flower than a joint paper can hold