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Additionally, untargeted metabolomics analysis of serial plasma samples from these patients were also conducted

In the presence of complex 2 the HPLC trace after 1 and 3 min showed two peaks at 1.12 min and 1.72 min, corresponding to GSO 3 H and GSSG, respectively

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For example, although cereblon expression is high in some cancers, a lower degradation activity of PROTACs is expected due to the lack of a DDB1/CUL4 protein

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In tumors with frequent TP53 mutations, which confer ferroptosis resistance, CHAC1 levels are often elevated