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HazanSDaveSPapoutsisAJDeshpandeNHowell MCJrMartinLM

4 and Supplementary Data 3)

doi: 10.1002/jat.2550010508 180 RushtonL.BaggaS.BevanR.BrownT

77 In turn, hyperinsulinemia due to IR in the liver and other target tissues can promote the production of liver fat, resulting in a vicious cycle

Glucocorticoid and progestogen use should be avoided

Additionally, GSK-J4, a dual inhibitor of histone lysine demethylase 6A/6B that prevents H3K27 demethylation, can suppress palmitic acid (PA)-induced hypersensitivity to ferroptosis by inhibiting ACSL4 expression and lipid peroxidation in cardiomyocytes[204]