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The supplement CDG is viewed as a potential clinical application for the regulation of estrogen metabolism and as a lipid-lowering agent (it helps maintain normal cholesterol levels)

G.MuthupillaiR.ChackoS.et al (2020)

Hypotheses 72 , 701705 (2009)

Mechanistic evidence relies heavily on animal studies (e.g., mouse neurotransmitter experiments) with insufficient large-scale human randomized controlled trials (RCTs) to confirm causality

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Contraindications: Uncontrolled asthma Known hypersensitivity to pilocarpine When miosis is undesirable Side Effects: The most frequent adverse experiences are a consequence of the expected pharmacologic effects of pilocarpine & include headache, sweating, flushing, increased urinary frequency