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The concurrent use of ketorolac tromethamine and therapy that affects hemostasis, including prophylactic low-dose heparin (2500 to 5000 units q12h), warfarin and dextrans have not been studied extensively, but may also be associated with an increased risk of bleeding

Namely, without upgrading, one sole episcleral vein function could not perform the whole function of aqueous fluid drainage [116,117,118,119,120,121]

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