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Summary RRs for dry snuff use are higher, ranging from 4 to 13, although the confidence intervals for these estimates are wide (Table 3)

| Johns Hopkins"

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The UK Committee on Toxicity (COT) highlighted significant reductions in levels of harmful and potentially harmful constituents (HPHCs) in the aerosol of HTP compared to cigarette smoke and stated that [t]here would likely be a reduction in risk for conventional smokers deciding to use heat-not-burn tobacco products instead of smoking cigarettes. COT added that [a] reduction in risk would also be experienced by bystanders where smokers switch to heat-not-burn tobacco products

More long-term studies are needed to look at the effects of HTPs, especially in COPD

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